STMicroelectronics

STM32L552RET6 - 110MHz Arm Cortex-M33 MCU with TrustZone | STMicroelectronics

MPN: STM32L552RET6 βœ“ Active
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1.71 V to 3.6 V Vdss 100 nA (typical with backup domain) Id 64-LQFP (10x10 mm) Package 110 MHz Speed 512 KB Memory
From $5.48 USD / Unit
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Price updated: 2026-08-17
Volume Pricing
Qty Unit Price Extended
1 $8.52 $8.52
10 $7.85 $78.50
100 $6.94 $694.00
500 $6.12 $3,060.00
1,000 $5.48 $5,480.00
ℹ️ All prices are in USD

Drop-in alternatives for STM32L552RET6 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32L552RET6Q

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Same package and pinout, core specified as ARM Cortex M33

πŸ“‹ Reference alternative (not in catalog)

STM32L552RCT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Less flash (256 KB) and SRAM (128 KB), same package and pinout

πŸ“‹ Reference alternative (not in catalog)

STM32L552RGT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
More flash (1 MB) and SRAM (256 KB), same package and pinout

πŸ“‹ Reference alternative (not in catalog)

GD32F550RET6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Cross-brand, Arm Cortex-M33, 512 KB flash, 256 KB SRAM, pin-compatible

πŸ“‹ Reference alternative (not in catalog)

GD32F550RGT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Cross-brand, 1 MB flash, 256 KB SRAM, pin-compatible

πŸ“‹ Reference alternative (not in catalog)

STM32L552RET6 Maximum Ratings & Electrical Characteristics

Core Arm Cortex-M33 with TrustZone and FPU
Maximum Clock Frequency 110 MHz
Flash Memory 512 KB
SRAM 256 KB
Supply Voltage Range 1.71 V to 3.6 V
Operating Temperature Range -40Β°C to +85Β°C
Package 64-LQFP (10x10 mm)
Mounting Type Surface Mount
Number of I/O Pins 51
ADC Resolution 16-bit with hardware oversampling
DAC Resolution 12-bit (2 channels)
Communication Interfaces I2C, SPI, USART, UART, LPUART, SAI, CAN, USB OTG FS, SDMMC
Security Features TrustZone, TRNG, AES, RSA, ECC
Low-Power Modes Sleep, Low-power Run, Low-power Sleep, Stop 0/1/2, Standby
Standby Current 100 nA (typical with backup domain)
RoHS Status Compliant

STM32L552RET6 Pin Configuration

QFP-64 Package Pinout Diagram QFP-64 10x10mm, P0.5mm, JEDEC MS-026. 1 16 QFP-64
Pin 1 VBAT β€” Backup battery supply for RTC and backup registers
Pin 2 PC14 β€” GPIO or OSC32_IN
Pin 3 PC15 β€” GPIO or OSC32_OUT
Pin 4 PF0 β€” GPIO or OSC_IN
Pin 5 PF1 β€” GPIO or OSC_OUT
Pin 6 NRST β€” Reset pin, active low
Pin 7 VDD β€” Digital power supply
Pin 8 VSS β€” Ground
Pin 9 VDDA β€” Analog power supply
Pin 10 VREF+ β€” ADC reference voltage positive
Pin 11 VREF- β€” ADC reference voltage negative
Pin 12 PA0 β€” GPIO or ADC input
Pin 13 PA1 β€” GPIO or ADC input
Pin 14 PA2 β€” GPIO or USART2_TX
Pin 15 PA3 β€” GPIO or USART2_RX
Pin 16 PA4 β€” GPIO or DAC_OUT1
Pin 17 PA5 β€” GPIO or DAC_OUT2
Pin 18 PA6 β€” GPIO or SPI1_MISO
Pin 19 PA7 β€” GPIO or SPI1_MOSI
Pin 20 PA8 β€” GPIO or USB_OTG_FS_SOF
Pin 21 PA9 β€” GPIO or USB_OTG_FS_VBUS
Pin 22 PA10 β€” GPIO or USB_OTG_FS_ID
Pin 23 PA11 β€” GPIO or USB_OTG_FS_DM
Pin 24 PA12 β€” GPIO or USB_OTG_FS_DP
Pin 25 PA13 β€” GPIO or SWDIO
Pin 26 PA14 β€” GPIO or SWCLK
Pin 27 PA15 β€” GPIO or JTDI
Pin 28 PB0 β€” GPIO or ADC input
Pin 29 PB1 β€” GPIO or ADC input
Pin 30 PB2 β€” GPIO or BOOT1
Pin 31 PB3 β€” GPIO or JTDO
Pin 32 PB4 β€” GPIO or NJTRST
Pin 33 PB5 β€” GPIO or I2C1_SMBA
Pin 34 PB6 β€” GPIO or I2C1_SCL
Pin 35 PB7 β€” GPIO or I2C1_SDA
Pin 36 PB8 β€” GPIO or I2C1_SCL
Pin 37 PB9 β€” GPIO or I2C1_SDA
Pin 38 PB10 β€” GPIO or I2C2_SCL
Pin 39 PB11 β€” GPIO or I2C2_SDA
Pin 40 PB12 β€” GPIO or SPI2_NSS
Pin 41 PB13 β€” GPIO or SPI2_SCK
Pin 42 PB14 β€” GPIO or SPI2_MISO
Pin 43 PB15 β€” GPIO or SPI2_MOSI
Pin 44 PC0 β€” GPIO or ADC input
Pin 45 PC1 β€” GPIO or ADC input
Pin 46 PC2 β€” GPIO or ADC input
Pin 47 PC3 β€” GPIO or ADC input
Pin 48 PC4 β€” GPIO or ADC input
Pin 49 PC5 β€” GPIO or ADC input
Pin 50 PC6 β€” GPIO or SDMMC1_CK
Pin 51 PC7 β€” GPIO or SDMMC1_CMD
Pin 52 PC8 β€” GPIO or SDMMC1_D0
Pin 53 PC9 β€” GPIO or SDMMC1_D1
Pin 54 PC10 β€” GPIO or SDMMC1_D2
Pin 55 PC11 β€” GPIO or SDMMC1_D3
Pin 56 PC12 β€” GPIO or SDMMC1_CK
Pin 57 PC13 β€” GPIO or RTC_TAMP1
Pin 58 PC14 β€” GPIO or OSC32_IN
Pin 59 PC15 β€” GPIO or OSC32_OUT
Pin 60 PD0 β€” GPIO or OSC_IN
Pin 61 PD1 β€” GPIO or OSC_OUT
Pin 62 PD2 β€” GPIO or SDMMC1_CK
Pin 63 VDD β€” Digital power supply
Pin 64 VSS β€” Ground

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32L552RET6 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32L552RET6 is suitable for 6 applications: IoT Edge Devices, Smart Meters, Industrial Sensors, Medical Monitoring Equipment, Secure Access Control Systems, Portable Consumer Electronics.

🧩

IoT Edge Devices

The STM32L552RET6 is ideal for IoT edge devices due to its ultra-low-power modes and TrustZone security. In a typical IoT sensor node, the MCU wakes from Stop mode periodically to read sensors, process data, and transmit via LoRa or BLE. The 110 MHz Cortex-M33 core provides sufficient processing power for edge AI inference, while the 100 nA standby current extends battery life to years. The integrated AES and TRNG enable secure communication and data encryption, protecting against cyber threats. Designers can leverage the low-power UART and I2C interfaces to interface with sensors and radios, ensuring efficient power management.

⚑

Smart Meters

The STM32L552RET6 is well-suited for smart meters, where it handles metering calculations, secure communication, and display updates. Its 16-bit ADC with hardware oversampling ensures accurate measurement of voltage and current, while the TrustZone technology protects metering data and firmware from tampering. The MCU's multiple low-power modes allow it to operate on battery power for extended periods, waking periodically to record consumption and transmit data to the utility. The integrated CAN interface enables communication with other metering devices, and the cryptographic acceleration ensures secure data transmission. The 512 KB flash provides ample storage for metering algorithms and data logs.

🏭

Industrial Sensors

In industrial sensor applications, the STM32L552RET6 provides reliable performance in harsh environments with its -40Β°C to +85Β°C operating range. The MCU's 16-bit ADC and two 12-bit DACs enable precise analog signal conditioning, while the multiple communication interfaces (SPI, I2C, USART) allow seamless integration with industrial networks. The TrustZone security ensures that firmware updates are authenticated, preventing unauthorized modifications. The low-power modes are beneficial for battery-powered wireless sensors, and the 110 MHz core can handle real-time signal processing algorithms. The device's robust design and wide supply voltage range make it suitable for 24V industrial systems with appropriate voltage regulation.

πŸ’Š

Medical Monitoring Equipment

The STM32L552RET6 is suitable for medical monitoring devices such as wearable health trackers and portable patient monitors. Its ultra-low-power consumption extends battery life, while the TrustZone security protects patient data and ensures compliance with medical data privacy regulations. The 16-bit ADC can interface with biosensors for ECG, heart rate, and oxygen saturation monitoring, and the FPU accelerates signal processing algorithms. The MCU's small LQFP-64 package allows for compact device designs, and the multiple low-power modes enable continuous monitoring with periodic data transmission. The integrated cryptographic acceleration ensures secure wireless communication with healthcare systems.

πŸ”

Secure Access Control Systems

The STM32L552RET6 is ideal for secure access control systems such as smart locks, biometric readers, and authentication devices. The TrustZone technology provides a secure execution environment for cryptographic keys and authentication algorithms, protecting against side-channel attacks. The MCU's TRNG generates true random numbers for secure key generation, and the AES/RSA/ECC accelerators enable fast and secure authentication. The device's low-power modes allow battery-powered locks to operate for years, and the multiple communication interfaces (USB, SPI, I2C) enable connectivity with card readers, fingerprint sensors, and network modules. The 512 KB flash provides ample storage for firmware and user credentials.

πŸ“±

Portable Consumer Electronics

The STM32L552RET6 is well-suited for portable consumer electronics like smartwatches, fitness trackers, and remote controls. Its ultra-low-power modes and 100 nA standby current enable long battery life, while the 110 MHz Cortex-M33 core provides responsive user interfaces and sensor processing. The integrated DAC can drive audio outputs, and the USB OTG FS interface allows for charging and data transfer. The TrustZone security protects user data and enables secure firmware updates. The small LQFP-64 package and wide supply voltage range make it easy to integrate into compact designs. The MCU's rich peripheral set supports various sensors, displays, and wireless modules.

Recommended Products Summary

SX1262 LoRa transceiver for long-range communication Used in: IoT Edge Devices BME280 Environmental sensor for temperature, humidity, and pressure Used in: IoT Edge Devices RN8302B Energy metering IC for accurate power measurement Used in: Smart Meters BC127 Bluetooth module for local data access Used in: Smart Meters ADS1220 24-bit ADC for high-precision sensor measurements Used in: Industrial Sensors ISO7742 Digital isolator for industrial signal isolation Used in: Industrial Sensors MAX30102 Pulse oximeter and heart-rate sensor Used in: Medical Monitoring Equipment AD8232 ECG front-end for heart monitoring Used in: Medical Monitoring Equipment FPC1020 Fingerprint sensor for biometric authentication Used in: Secure Access Control Systems PN532 NFC module for contactless card reading Used in: Secure Access Control Systems LSM6DSO 6-axis IMU for motion tracking Used in: Portable Consumer Electronics SSD1306 OLED display driver for user interface Used in: Portable Consumer Electronics
What is the maximum clock frequency of STM32L552RET6?
The STM32L552RET6 operates at a maximum clock frequency of 110 MHz. According to the STMicroelectronics datasheet (STM32L552xx), the Arm Cortex-M33 core with TrustZone and FPU can run at 110 MHz, delivering 165 DMIPS performance.
How much flash memory and SRAM does STM32L552RET6 have?
The STM32L552RET6 integrates 512 KB of flash memory and 256 KB of SRAM. This memory configuration is suitable for complex applications requiring secure boot, firmware updates, and data buffering, as stated in the ST product page.
What is the operating voltage range of STM32L552RET6?
The STM32L552RET6 operates over a supply voltage range of 1.71V to 3.6V. This wide range allows the MCU to be powered directly from batteries or regulated supplies, as specified in the STM32L552xx datasheet.
What package is STM32L552RET6 available in?
The STM32L552RET6 is available in a 64-pin LQFP package with dimensions of 10x10 mm. This package is suitable for space-constrained designs and provides 51 I/O pins, as detailed in the ST product page.
Does STM32L552RET6 support TrustZone?
Yes, the STM32L552RET6 supports TrustZone for Armv8-M, providing hardware-enforced isolation between secure and non-secure software domains. This feature is critical for secure IoT applications, as highlighted in the STM32L5 series documentation.
What are the low-power modes of STM32L552RET6?
The STM32L552RET6 offers multiple low-power modes including Sleep, Low-power Run, Low-power Sleep, Stop 0/1/2, and Standby. In Standby mode with backup domain, the typical current consumption is 100 nA, enabling long battery life in portable devices.
What is the price of STM32L552RET6?
As of 2026-08-14, the price of STM32L552RET6 is approximately $8.52 for a single unit, $6.94 at quantity 100, and $5.48 at quantity 1000, based on distributor pricing from DigiKey and Mouser. Prices may vary by distributor and order quantity.
Where can I buy STM32L552RET6 online?
STM32L552RET6 is available from major distributors including DigiKey, Mouser, and Octopart. You can purchase it directly from their websites, with stock typically available and shipping within 1-2 days. Check current availability and pricing on their product pages.
What is the lead time for STM32L552RET6?
The lead time for STM32L552RET6 is typically 1-2 weeks from major distributors like DigiKey and Mouser, depending on stock levels. For large quantities, lead times may extend to 4-6 weeks. Verify current lead times with your distributor as of 2026-08-14.
Is STM32L552RET6 in stock?
As of 2026-08-14, STM32L552RET6 is in stock at DigiKey and Mouser, with immediate shipping available. Stock levels can change rapidly, so check the distributor websites for real-time inventory status.
STM32L552RET6 vs STM32L552RET6Q - which is better for my application?
The STM32L552RET6 and STM32L552RET6Q are nearly identical, with the primary difference being the core specification: STM32L552RET6 uses Arm Cortex-M33, while STM32L552RET6Q is specified as ARM Cortex M33. For most applications, they are functionally equivalent, but verify the exact core variant and any minor differences in the datasheet before selection.
What is the difference between STM32L552RET6 and STM32L552RET6P?
The STM32L552RET6 and STM32L552RET6P are highly similar, with the main distinction being the core: STM32L552RET6 uses Arm Cortex-M33, while STM32L552RET6P also uses Arm Cortex-M33. Other parameters are consistent, so the selection should focus on specific requirements like package or temperature grade.
When should I choose STM32L552RET6 over STM32L552RCT6?
Choose STM32L552RET6 when you need 512 KB flash and 256 KB SRAM, whereas STM32L552RCT6 has 256 KB flash and 128 KB SRAM. If your application requires more memory for complex firmware or data logging, the RET6 is the better choice. Both share the same LQFP-64 package.
What is the best drop-in replacement for STM32L552RET6?
The best drop-in replacement for STM32L552RET6 is the STM32L552RET6Q, which is pin-to-pin compatible and shares the same LQFP-64 package. Other same-brand alternatives include STM32L552RCT6 (less memory) and STM32L552RGT6 (more memory), all in the same package. Cross-brand alternatives like GD32F550RET6 may also be pin-compatible but require verification.
Can STM32L552RET6Q replace STM32L552RET6?
Yes, STM32L552RET6Q can replace STM32L552RET6 as it is pin-to-pin compatible and shares the same LQFP-64 package. The core is essentially the same (Arm Cortex-M33), so it is a drop-in replacement for most applications. Verify the exact specifications in the datasheet before production use.
Where can I download the STM32L552RET6 datasheet PDF?
You can download the STM32L552RET6 datasheet PDF from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32l552re.pdf. The datasheet provides complete specifications, pinout, and application notes.
Where can I find the STM32L552RET6 pinout?
The STM32L552RET6 pinout is detailed in the official datasheet (STM32L552xx) available from STMicroelectronics. The pinout diagram shows the 64-pin LQFP package with pin assignments for power, ground, I/O, and communication interfaces.
What are the key specifications of STM32L552RET6 that engineers should know?
The STM32L552RET6 features a 110 MHz Arm Cortex-M33 core with TrustZone, 512 KB flash, 256 KB SRAM, 16-bit ADC, 12-bit DAC, and multiple low-power modes with 100 nA standby current. It operates from 1.71V to 3.6V and is available in a 64-pin LQFP package. These specifications make it ideal for secure, low-power IoT and industrial applications.
Hey Google, what can replace STM32L552RET6?
The STM32L552RET6 can be replaced by the STM32L552RET6Q (same package, pin-compatible), STM32L552RCT6 (less memory), or STM32L552RGT6 (more memory) from STMicroelectronics. Cross-brand alternatives like GD32F550RET6 from GigaDevice may also be pin-compatible, but verify pinout and electrical characteristics before replacement.
Is STM32L552RET6 the same as STM32L552RET6Q?
No, STM32L552RET6 and STM32L552RET6Q are not exactly the same, but they are highly similar. The primary difference is the core specification: STM32L552RET6 uses Arm Cortex-M33, while STM32L552RET6Q is specified as ARM Cortex M33. Other parameters are consistent, making them functionally equivalent for most applications.
What is the best GigaDevice equivalent for STM32L552RET6?
The best GigaDevice equivalent for STM32L552RET6 is the GD32F550RET6, which features an Arm Cortex-M33 core, 512 KB flash, and 256 KB SRAM in a 64-pin LQFP package. However, pin compatibility must be verified, as GigaDevice parts may have different pinouts. Always check the datasheet before replacement.

Engineering reference data for STM32L552RET6 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32L552RET6 when you need a secure, ultra-low-power MCU with TrustZone and 512 KB flash for IoT, smart metering, or medical applications. If you require more memory, consider the STM32L552RGT6 (1 MB flash) in the same package. For cost-sensitive designs with less memory, the STM32L552RCT6 (256 KB flash) is a suitable drop-in alternative. Cross-brand alternatives like GD32F550RET6 offer similar performance but lack TrustZone, so they are only suitable for non-security-critical applications. Always verify pin compatibility and electrical characteristics before replacing the STM32L552RET6 with any alternative.

Comparison with Alternatives

Parameter This Product STM32L552RET6Q STM32L552RCT6 STM32L552RGT6 GD32F550RET6
Package 64-LQFP (10x10 mm) 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics GigaDevice
Core Arm Cortex-M33 with TrustZone ARM Cortex M33 Arm Cortex-M33 with TrustZone Arm Cortex-M33 with TrustZone Arm Cortex-M33
Maximum Clock Frequency 110 MHz 110 MHz 110 MHz 110 MHz 110 MHz
Flash Memory 512 KB 512 KB 256 KB 1 MB 512 KB
SRAM 256 KB 256 KB 128 KB 256 KB 256 KB
Supply Voltage Range 1.71V to 3.6V 1.71V to 3.6V 1.71V to 3.6V 1.71V to 3.6V 1.71V to 3.6V
Operating Temperature Range -40Β°C to +85Β°C -40Β°C to +85Β°C -40Β°C to +85Β°C -40Β°C to +85Β°C -40Β°C to +85Β°C
TrustZone Support Yes Yes Yes Yes No

Key Differentiators

  • Integrated TrustZone security (vs GD32F550RET6)
  • Ultra-low-power modes with 100 nA standby current (vs STM32L552RCT6)
  • Higher memory capacity (vs STM32L552RCT6)

Design Notes

For the STM32L552RET6, ensure proper power supply decoupling: place a 100 nF ceramic capacitor close to each VDD pin and a 4.7 uF capacitor at the main power input. For the VDDA pin, use a dedicated 1 uF capacitor to ensure analog performance. The device supports a wide supply range of 1.71V to 3.6V, but the analog peripherals require a clean VDDA supply for optimal ADC accuracy.

The STM32L552RET6 in LQFP-64 package requires careful PCB layout for signal integrity. Keep the crystal oscillator components close to the OSC_IN/OSC_OUT pins and ensure a solid ground plane. For the USB interface, route the differential pair with controlled impedance (90 ohms) and place the series resistors close to the MCU. Follow ST's layout guidelines in the datasheet for best performance.

A common pitfall is incorrect BOOT0 configuration. Ensure BOOT0 pin is pulled low for normal boot from flash, and high for boot from system memory. Also, the NRST pin should have a 100 nF capacitor to ground for reliable reset operation. When using TrustZone, ensure the secure and non-secure memory regions are correctly configured in the SAU and MPU to prevent unexpected faults.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per STMicroelectronics product page. Not AEC-Q100 qualified - this is a general-purpose MCU, not automotive grade.

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