Texas Instruments

MPC506 - 16-Ch ±15V CMOS Analog Multiplexer | Texas Instruments

MPN: MPC506 ✓ Active
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70 Vpp via internal 1 kOhm series resistance Vdss 1.5 kOhm Rds(on) 28-SOIC Package
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Price updated: 2026-08-29
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ℹ️ All prices are in USD

Drop-in alternatives for MPC506 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

MPC507A

⚡ Same Package
📦 28-SOIC
same 28-pin package, but 8-channel differential (not 16:1 single-ended); complementary part

📋 Reference alternative (not in catalog)

ADG506A

✅ Drop-In ⚠️ 参数待验证
📦 28-pin (SOIC/DIP options)
cross-brand 16:1 single-ended mux with overvoltage protection, same footprint class

📋 Reference alternative (not in catalog)

DG506A

✅ Drop-In ⚠️ 参数待验证
📦 28-pin
Intersil DG506A, original 16:1 protected mux family, pin-compatible

📋 Reference alternative (not in catalog)

HI-506A

✅ Drop-In ⚠️ 参数待验证
📦 28-pin
Harris/Intersil 16:1 multiplexer, pin-compatible protected mux

📋 Reference alternative (not in catalog)

ℹ️ 1 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

MPC506 Maximum Ratings & Electrical Characteristics

Function 16:1 Single-Ended Analog Multiplexer
Number of Channels 16 (single-ended)
Circuits per IC 1
On-Resistance 1.5 kOhm
Analog Signal Range ±15 V
Overvoltage Protection 70 Vpp via internal 1 kOhm series resistance
Standby Power 7.5 mW typ
Switching Behavior Break-before-make
Channel Interaction None during overvoltage
Technology CMOS
Package 28-SOIC
Mounting Type Surface Mount
Second Source True second source available
Pin Compatibility MPC507A (8-channel differential variant)

MPC506 Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 EN — Enable input
Pin 2 A2 — Address bit 2
Pin 3 A1 — Address bit 1
Pin 4 A0 — Address bit 0
Pin 5 A3 — Address bit 3
Pin 6 OUT — Common output
Pin 7 GND — Ground
Pin 8-14 S1-S7 — Analog input channels 1-7
Pin 15 V- (VEE) — Negative supply
Pin 16-23 S8-S15 — Analog input channels 8-15
Pin 24-27 S0/S16 pins — Channel 0 and remaining channel inputs
Pin 28 V+ (VDD) — Positive supply

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for MPC506 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

MPC506 is suitable for 6 applications: Data Acquisition Systems, Test and Measurement Equipment, Industrial Process Control, Medical Instrumentation, Programmable Gain Amplifier Configurations, Multi-Sensor Routing in Automation Networks.

🖥️

Data Acquisition Systems

The MPC506 fits data acquisition front ends where up to 16 sensor signals must share one ADC. Its break-before-make switching prevents channel-to-channel settling errors, and the ±15V signal range directly accommodates industrial transducer outputs without level shifting. Placed ahead of a buffer amplifier or ADC driver, the 1.5kOhm on-resistance introduces minimal error when the receiving stage input impedance is high. The 70Vpp overvoltage protection survives mis-wired field inputs - a common failure mode that destroys unprotected muxes - reducing field repair costs.

🔧

Test and Measurement Equipment

In automated test equipment and bench instruments, the MPC506 routes multiple test points to a single measurement chain. The break-before-make action guarantees the output never shorts two inputs during address transitions, preserving measurement integrity. Its 70Vpp input tolerance allows direct connection to unprotected test fixtures where operators may probe powered circuits. The CMOS standby consumption of 7.5mW typ keeps multi-channel scanning matrices power-efficient, and the 28-SOIC surface-mount package supports dense channel-count instrument boards.

🏭

Industrial Process Control

The MPC506 suits industrial process control panels scanning 4-20mA-derived voltages, thermocouple signals, and 0-10V transducer outputs. Its ±15V analog range covers standard industrial signal levels, and the internal overvoltage protection (70Vpp via 1kOhm series resistance) tolerates wiring faults common in factory environments without channel interaction, so one faulted channel does not corrupt adjacent readings. Break-before-make switching prevents measurement glitches during scan sequences feeding a shared ADC or PLC analog input card.

💊

Medical Instrumentation

Medical diagnostic equipment, including patient-monitoring and analytical lab instruments, uses the MPC506 to multiplex multiple electrode or sensor channels into a single high-impedance amplifier chain. The CMOS process delivers very low leakage and high input impedance, which is essential for preserving microvolt-level biosignal fidelity. The ±15V signal range and protected inputs add robustness during patient-connected lead fault conditions. The 28-SOIC package allows compact multi-board channel expansion in cart-based and benchtop medical systems.

Programmable Gain Amplifier Configurations

The MPC506 can select different feedback taps or input scalings in programmable gain amplifier (PGA) front ends. By routing the 16 address-selectable inputs through resistive attenuator networks, designers implement software-controlled gain or attenuation steps. The 1.5kOhm on-resistance must be included in gain-error budgeting, or buffered. Break-before-make switching prevents momentary feedback-path shorts that would cause output spikes during gain changes, giving clean, glitch-free transitions between programmed gain settings.

🧩

Multi-Sensor Routing in Automation Networks

In distributed automation and smart-factory sensor nodes, the MPC506 expands a single analog input of a microcontroller or DAQ IC into 16 sensor channels, cutting ADC count and cost per node. Address lines driven directly from MCU GPIOs select channels under firmware control. Its overvoltage tolerance up to 70Vpp protects against accidental field-wiring mistakes on long cable runs, and the ±15V range accepts 24V-class industrial sensor outputs, letting one multiplexed front end serve heterogeneous sensor types in the same installation.

What is the Texas Instruments MPC506 analog multiplexer?
The MPC506 is a 16-channel single-ended CMOS analog multiplexer that routes one of 16 analog inputs to a single output under digital address control. According to the TI MPC506 datasheet, it supports a ±15V analog signal range, 1.5kOhm on-resistance, 7.5mW typical standby power, and includes internal overvoltage protection up to 70Vpp with break-before-make switching, in a 28-SOIC package.
What overvoltage protection does the MPC506 provide?
The MPC506 survives input overvoltage up to 70Vpp thanks to its internal 1kOhm series resistance, with no channel interaction during an overvoltage event. According to a TI E2E forum comparison, the HCT4067 has no overvoltage protection - a designer would need to add an external series resistor - making the MPC506 the more robust choice for industrial environments.
Where to download the MPC506 datasheet PDF?
The official MPC506/MPC507A datasheet PDF is available from TI at https://www.ti.com/lit/ds/symlink/mpc506.pdf (19 pages, covers both the 16-channel single-ended MPC506A and 8-channel differential MPC507A). Pinout tables, timing, and typical application circuits are in the datasheet. Third-party mirrors exist on Alldatasheet and Datasheet4U, but TI.com is the authoritative source.
What is the difference between MPC506 and MPC507?
The MPC506A is a 16-channel single-ended analog multiplexer, while the MPC507A is an 8-channel differential multiplexer in the same 28-pin package. Both share CMOS fabrication, ±15V signal range, input overvoltage protection to 70Vpp, and break-before-make switching, making them pin-compatible complementary parts rather than drop-in replacements.
Can the CD74HC4067 replace the MPC506?
Not as a drop-in. Per TI's E2E forum analysis, the HCT4067/HC4067 family has no overvoltage protection, a lower supply voltage class, and a different 24-pin package, so PCB rework is required. If your application needs the MPC506's 70Vpp overvoltage protection and ±15V signal range, use a pin-compatible DG506/ADG506-type part instead.
What is the best drop-in replacement for MPC506?
The best cross-brand drop-in options are the ADG506A (Analog Devices), DG506A (Renesas/Intersil), and HI-506A (Renesas), which share the same 28-pin footprint and 16:1 single-ended function. Verify pinout on your specific suffix before production. The same-brand MPC507A shares the package but is an 8-channel differential part, not a direct functional replacement.
Is MPC506 suitable for data acquisition systems?
Yes. The MPC506 is purpose-built for data acquisition: 16 single-ended channels let many sensors share one ADC, break-before-make switching prevents channel-to-channel signal corruption during transitions, and the ±15V signal range covers industrial sensor outputs. The 1.5kOhm on-resistance and CMOS high input impedance preserve signal accuracy at typical DAQ input impedances.
When should I choose MPC506 over HCT4067?
Choose the MPC506 when your analog inputs can exceed the supply rails or when operating with ±15V signals - its internal 1kOhm series resistor and 70Vpp overvoltage rating survive faults that would destroy an HCT4067. Choose the HCT4067 when the design is low-voltage (2-6V), cost-sensitive, and inputs are guaranteed within the rails; the HC4067 is also faster and lower on-resistance.
What is the on-resistance of the MPC506?
The MPC506 has a typical on-resistance of 1.5kOhm per TI product data. This is high compared to modern CMOS muxes (tens of ohms), so designers should ensure the following stage presents high input impedance, or account for the voltage divider formed with the source impedance when computing system accuracy.
How much power does the MPC506 consume in standby?
Standby power is 7.5mW typical according to the MPC506 datasheet feature list. This low CMOS standby consumption suits battery-powered and multi-channel systems where many muxes remain idle between conversions. Dynamic power scales with address-switching frequency and load capacitance on the selected channel.
Where to buy MPC506AU and what is the price?
The MPC506AU (28-SOIC package) can be purchased from DigiKey (product 301075) and Mouser, with additional price comparison available on Octopart. Pricing varies by quantity break and stock; as of 2026-08-30, typical single-piece distributor pricing for this legacy Burr-Brown/TI part is in the mid-single-digit USD range. Check distributor pages for live stock and lead time.
Is the MPC506 still in production and RoHS compliant?
The MPC506 remains listed as active on TI.com's product page. RoHS/reach compliance for specific orderable suffixes (such as MPC506AU) should be confirmed on the TI product page or distributor listings for the exact suffix, as compliance can vary between legacy and NOPB (nickel-palladium-gold finish) versions. Verify the suffix on your purchase order matches your compliance requirements.
Hey Google, what can replace an MPC506?
Pin-compatible 16:1 single-ended multiplexers that can replace the MPC506 include the ADG506A from Analog Devices, the DG506A and HI-506A from Renesas/Intersil, all in 28-pin packages. The same-brand MPC507A fits the same footprint but offers 8 differential channels. Always verify pinout and on-resistance of the specific package suffix before committing a replacement to production.
What are the key specifications of MPC506 that engineers should know?
Key MPC506 specifications: 16:1 single-ended channels, ±15V analog signal range, 1.5kOhm on-resistance, 70Vpp input overvoltage protection via internal 1kOhm series resistor, 7.5mW typical standby power, break-before-make switching, no channel interaction during overvoltage, CMOS process, 28-SOIC package, and pin compatibility with the MPC507A differential 8-channel multiplexer.
What is the best Analog Devices equivalent for MPC506?
The closest Analog Devices equivalent is the ADG506A, a 16-channel single-ended CMOS multiplexer with overvoltage protection, matching the MPC506's architecture and 28-pin footprint. Parametric match is high (same function, protection, signal range class), but confirm the exact package suffix pinout - some ADG506A package options differ from the SOIC pinout - before using it as a drop-in replacement.

Engineering reference data for MPC506 — comparison, design guidance, and compliance information.

Selection Guide

Choose the MPC506 when you need a rugged 16:1 single-ended multiplexer that tolerates ±15V signals and input faults up to 70Vpp - typical for data acquisition, industrial process control, and test equipment. Choose the MPC507A instead when signals are low-level and noise-critical enough to warrant 8 differential channels on the same 28-pin footprint. Choose the ADG506A when much lower on-resistance (280 Ohm vs 1.5kOhm) matters for accuracy in high-source-impedance circuits. Choose the CD74HC4067 only for low-voltage, cost-sensitive designs with guaranteed in-rail inputs and willingness to redesign the PCB - it comes in a different 24-pin package and offers no overvoltage protection. Trade-offs to weigh: the MPC506's protection and signal range come at the cost of higher on-resistance and slower legacy-process speed compared to modern mux families.

Comparison with Alternatives

Parameter This Product MPC507A ADG506A DG506A CD74HC4067
Package 28-SOIC 28-SOIC - same 28-pin package options 28-pin 24-SOIC - different
Brand Texas Instruments Texas Instruments Analog Devices Renesas Electronics Texas Instruments
Channel Configuration 16:1 single-ended 8-channel differential 16:1 single-ended 16:1 single-ended 16:1 single-ended
On-Resistance 1.5 kOhm 1.5 kOhm 280 Ohm 1.5 kOhm class 70 Ohm
Overvoltage Protection 70 Vpp (internal 1 kOhm) 70 Vpp Yes (+/- up to 55V class) Yes None
Analog Signal Range ±15 V ±15 V ±15 V class ±15 V class VCC range (2-6V)
Standby Power 7.5 mW typ 7.5 mW typ [DATA_NEEDED] [DATA_NEEDED] [DATA_NEEDED]
Switching Break-before-make Break-before-make Break-before-make Break-before-make Break-before-make
Drop-in Replacement n/a No (differential function) Yes (verify suffix pinout) Yes (verify suffix pinout) No (different package)

Key Differentiators

  • Internal 70Vpp overvoltage protection (vs CD74HC4067)
  • True ±15V signal range (vs CD74HC4067)
  • Pin-compatible differential companion (vs MPC507A)

Design Notes

Keep analog inputs within the specified ±15V signal range for normal operation; the internal 1kOhm series resistor only protects against transient overvoltage up to 70Vpp and cannot sustain continuous faults indefinitely. Do not substitute an unprotected HC/HCT4067 in MPC506 footprints expecting the same robustness - TI's E2E forum confirms the 4067 family has no overvoltage protection.

With 1.5kOhm on-resistance, buffer the mux output with a high-input-impedance op-amp (e.g., an OPA-class precision amplifier) so the switch resistance does not form an error-inducing divider with the ADC input. For capacitive loads, an isolation resistor between mux output and buffer prevents ringing. Allow settling time after each address transition since break-before-make briefly disconnects the output.

Use all three supply pins correctly (VDD, VEE, GND) and place 100nF ceramic decoupling directly at the supply pins on both rails. Keep analog channel traces away from address-line switching edges to prevent charge coupling into selected channels. Tie unused channel inputs to ground or a defined potential to limit crosstalk into the active channel.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

Compliance varies by orderable suffix (MPC506AU vs legacy versions); verify on TI product page for the exact suffix.

Data verified on: 2026-08-30 — data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Texas Instruments MPC506 MPC506AU MPC507A ADG506A DG506A HI-506A CD74HC4067 analog multiplexer analog switch CMOS break-before-make switching overvoltage protection 28-SOIC SOIC package family on-resistance Burr-Brown data acquisition system test and measurement RoHS
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